| 产品详情 |
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| Antigenic Specificity | ALOXE3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ALOXE3 Polyclonal Antibody. ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. |
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| Immunogen | n/a |
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| Other Names | E-LOX, eLOX3, e-LOX-3, epidermal lipoxygenase, epidermis-type lipoxygenase 3 |
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| Gene, Accession # | Entrez: 23801, 59344; Uniprot: Q9BYJ1, Q9WV07 |
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| Catalog # | PA5-23953 |
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| Price | |
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| Order / More Info | ALOXE3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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