产品名称 ZLN 024 hydrochloride from TOCRIS BIOSCIENCE
产品货号 5285/10
产品价格 现货询价,电话:010-67529703
产品规格 10 mg
产品品牌 TOCRIS BIOSCIENCE
产品概述
产品详情
Edit&nbsp
Product NameZLN 024 hydrochloride
DescriptionAllosteric AMP-activated protein kinase (AMPK) activator; allosterically stimulates active AMPK heterotrimers, increasing the activity of α1β1γ1 by 1.5-fold and α2β1γ1 by 1.7-fold (EC50 values are 0.42 and 0.95 μM, respectively). Inhibits dephosphorylation of AMPK Thr-172 by PP2Cα. Stimulates glucose uptake and fatty acid oxidation without increasing the ADP/ATP ratio. Also decreases fatty acid synthesis and glucose output in primary hepatocytes. Improves glucose tolerance and decreases cholesterol content in db/db mice. Purity 99%. MW (observed): 361.69
Size10 mg
Concentrationn/a
Applicationsn/a
Other Names2-[[2-(2-Bromo-4-methylphenoxy)ethyl]thio]pyrimidine hydrochloride
Gene, Accession, CAS #n/a
Catalog #5285/10
Price
Order / More InfoZLN 024 hydrochloride from TOCRIS BIOSCIENCE
Product Specific Referencesn/a
产品资料