| 产品详情 |
| Edit |   |
|---|
| Product Name | Zoniporide dihydrochloride |
|---|
| Description | Sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor that displays selectivity over other NHE isoforms (Ki values are 14, 2200 and 220000 nM for human NHE1, human NHE2 and rat NHE3 respectively). Inhibits NHE1 dependent 22Na+ uptake in vitro (IC50 = 14 nM) and provides cardioprotection from myocardial ischemic injury in vivo (EC50 = 0.25 nM). Also inhibits MMP2/9 activity and invasion in breast cancer cells. Purity 99%. MW (observed): 393.27 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [1-(Quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine dihydrochloride. CP 597396 |
|---|
| Gene, Accession, CAS # | CAS: 241799-10-0 |
|---|
| Catalog # | 2727/50 |
|---|
| Price | |
|---|
| Order / More Info | Zoniporide dihydrochloride from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 21887327, 24466344 |
|---|
| 产品资料 |
|
|