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Product Name | Aucubin |
Description | An iridoid glycoside with diverse biological activities; dose-dependently inhibits the IgE-stimulated secretion of IL-6 and TNF-α by RBL-2H3 mast cells (IC50s = 0.19 and 0.1 µg/ml, respectively); reduces UVB-induced expression of MMP-1 by 57% in HS68 cells at 0.01 µg/ml; dose-dependently reduces ROS and MDA levels in HS68 cells at 0.01-1 µg/ml; decreases the breathing frequency, increases lung dynamic compliance, alleviates parenchymal fibrotic changes, and reduces expression of TGF-β1 and α-SMA in a mouse model of bleomycin-induced pulmonary fibrosis at 5 mg/kg; reduces blood glucose levels, lipid peroxidation in the liver and kidneys, the number of errors made in a Y-maze, and enhances neuronal survival in rats with streptozotocin-induced diabetes at 5 mg/kg |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 11019-65-1 11019-67-3 22593-66-4 99005-46-6 aucubine aucubosid rhimantin Eucommia IL6 TNFα RBL2H3 MMP1 HS-68 TGFβ1 αSMA |
Gene, Accession, CAS # | CAS: 479-98-1 |
Catalog # | 24928-50 |
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Order / More Info | Aucubin from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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