产品详情 |
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Antigenic Specificity | DHCR24 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DHCR24 Polyclonal Antibody. This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. |
Immunogen | n/a |
Other Names | DCE, Nbla03646, SELADIN1, seladin-1, 3 beta-hydroxysterol delta 24-reductase, 3-beta-hydroxysterol delta-24-reductase, delta(24)-sterol reductase, desmosterol-to-cholesterol enzyme, diminuto/dwarf1 homolog, seladin 1, selective AD indicator 1 |
Gene, Accession # | Entrez: 1718, 74754; Uniprot: Q15392, Q8VCH6 |
Catalog # | PA5-27944 |
Price | |
Order / More Info | DHCR24 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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