Edit |   |
Antigenic Specificity | DHCR24 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DHCR24 Polyclonal Antibody. DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in DHCR24 gene have been associated with desmosterolosis. Also, reduced expression of DHCR24 gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. |
Immunogen | n/a |
Other Names | Diminuto/dwarf1 homolog; Seladin-1; 3-beta-hydroxysterol delta-24-reductase; 24-dehydrocholesterol reductase; DHCR24; KIAA0018 |
Gene, Accession # | Entrez: 1718; Uniprot: Q15392 |
Catalog # | PA5-12457 |
Price | |
Order / More Info | DHCR24 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |