| 产品详情 |
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| Antigenic Specificity | Lamin A/C (mutant 453W) |
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| Clone | 5H8-B4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: Assay-dependent, Immunofluorescence: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:32,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Lamin A/C (mutant 453W) Monoclonal Antibody (5H8-B4). Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type |
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| Immunogen | n/a |
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| Other Names | Prelamin-A/C; 70 kDa lamin; LMN1; LMNA; Renal carcinoma antigen NY-REN-32; mutant 453W; Lamin A+C mutant |
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| Gene, Accession # | Entrez: 4000; Uniprot: P02545 |
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| Catalog # | MA5-18063 |
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| Price | |
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| Order / More Info | Lamin A/C (mutant 453W) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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