产品详情 |
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Antigenic Specificity | NY-ESO-1 |
Clone | E978 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 2.5 µg/mL, Immunohistochemistry: Assay Dependent, Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NY-ESO-1 Monoclonal Antibody (E978). NY-ESO-1, a member of the cancer/testis (CT) family, is a tumor-specific shared antigen with distinctive immunogenicity. Cancer/testis antigens are expressed in a range of malignant neoplasms such as melanoma and carcinomas of the breast, ovary and lung, but not in normal tissue except in testis. NY-ESO-1 reactivity in testis is restricted germ cells, particularly in the spermatogonia. NY-ESO-1 is a classic CT antigen discovered during a SEREX analysis of esophageal cancer. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen. It is a 22-23 KDa hydrophobic protein. |
Immunogen | n/a |
Other Names | Cancer/testis antigen 1, Autoimmunogenic cancer/testis antigen NY-ESO-1, Cancer/testis antigen 6.1, CT6.1, L antigen family member 2, LAGE-2, CTAG1A, CTAG, CTAG1, ESO1, LAGE2, LAGE2A, CTAG1B, LAGE2B |
Gene, Accession # | Entrez: 246100; Uniprot: P78358 |
Catalog # | 35-6200 |
Price | |
Order / More Info | NY-ESO-1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15756003, 16003736, 16557580, 16751374, 16773077, 17019710, 17096152, 17294444, 17893560, 18307538, 18663444, 18923710, 18942708, 19398128, 20067767, 20103663, 21626030, 21747904, 21754986, 22140550, 22207316, 22739387, 22740853, 23529156, 24021875, 24085111, 24584817, 24739759, 25260825, 25412843, 26447882, 26883197, 26942053, 28588683 |
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