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Product Name | MASP-2, Human, ELISA kit |
Description | MASP-2 is a MBL associated serine protease. Mannan-binding lectin (MBL) and ficolins, in complex with MASPs, are capable of activating the complement system, thus mediating the destruction of infectious agents. After oligomerisation of MBL (or L-Ficolin) MASP-2 will be bound and activated. Activated MASP-2 cleaves C4 and C2 and is crucial for the activation of downstream complement components. MASP-2 deficiency will result in an increased susceptibility for infections (e.g. leukemia patients in chemotherapy are at high risk of serious infections). Even more so then MBL deficiency, because MASP-2 is also required for complement activation by H- and L-ficolin. The ELISA detects MASP-2 in serum and plasma. The MASP-2 levels in plasma from healthy individuals range from 170 to 1196 ng/ml. |
Size | 2 x 96 det. |
Concentration | n/a |
Applications | Immunoassay |
Other Names | Sandwich ELISA kit, EIA, enzyme immunoassay, assay |
Gene, Accession, CAS # | n/a |
Catalog # | HK326-02 |
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Order / More Info | MASP-2, Human, ELISA kit from HYCULT BIOTECH |
Product Specific References | n/a |
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