| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | FBW7 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 10 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunoprecipitation: 2-5 µg/mg lysate |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | FBW7 Polyclonal Antibody. Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of malignancies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E. |
|---|
| Immunogen | n/a |
|---|
| Other Names | AGO, archipelago, Archipelago homolog, archipelago homolog (Drosophila), CDC4, F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase, F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila), F-box and WD-40 domain-containing protein 7, F-box protein FBW7, F-box protein FBX30, F-box protein SEL-10, FBW6, FBW7, FBX30, FBXO30, FBXW6, FLJ11071, hAgo, hCdc4, homolog of C elegans sel-10, SEL10, SEL-10 |
|---|
| Gene, Accession # | Entrez: 55294; Uniprot: Q969H0 |
|---|
| Catalog # | A301-720A-T |
|---|
| Price | |
|---|
| Order / More Info | FBW7 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|