| 产品详情 |
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| Antigenic Specificity | MEK3 |
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| Clone | 1H8L14 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MEK3 Antibody (1H8L14), ABfinity™ Rabbit Monoclonal. MKK3 (MEK3) is a dual specificity protein kinase that belongs to the MAP kinase kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. |
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| Immunogen | n/a |
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| Other Names | MEK3, MKK3, PRKMK3, SKK2 |
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| Gene, Accession # | Entrez: 5606; Uniprot: P46734 |
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| Catalog # | 702225 |
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| Price | |
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| Order / More Info | MEK3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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