| 产品详情 |
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| Antigenic Specificity | MEK2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MEK2 Polyclonal Antibody. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogen |
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| Immunogen | n/a |
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| Other Names | MAPKK2, MKK2, PRKMK2, MAP2K2 |
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| Gene, Accession # | Entrez: 26396, 5605, 58960; Uniprot: P36506, P36507, Q63932 |
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| Catalog # | PA1-29852 |
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| Price | |
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| Order / More Info | MEK2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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