产品名称 Human tPA activity ELISA Kit from EAGLE BIOSCIENCES INC.
产品货号 TPA39-K01
产品价格 现货询价,电话:010-67529703
产品规格 1 x 96 well
产品品牌 EAGLE BIOSCIENCES INC.
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Product NameHuman tPA activity ELISA Kit
DescriptionFirst the biotinylated PAI-1 binds to the avidin coated wells. Next, active tPA present in the standard or unknown, complexes with PAI-1. Inactive or complexed tPA is removed in a subsequent wash step. A primary antibody specific for tPA is then added to each well followed by the HRP conjugated secondary antibody. The bound conjugated secondary antibody is detected by the addition of substrate, which generates an optimal color after 10 minutes. Quantitative test results may be obtained by the measure and comparison of the sample and standard absorbance readings when read with a microplate reader at 450 nm. Sample Types: biological fluids. Range: 0.1 - 5 ng/ml. Sensitivity: 0.006 IU/µL. Time: 2.5 hours • Tissue-type Plasminogen Activator (tPA) is a member of the serine proteinase family. tPA functions to lyse fibrin clots into soluble plasmin fragments. tPA is active in two forms, single chain and two chain. The two-chain tPA is created via interaction with the plasmin product cleaving the single chain. This two-chain form is regarded as the more active form. Both single chain and two-chain tPA are complexable with PAI-1. PAI-1 acts as an inhibitor for tPA by binding to the tPA and thus stifling its ability to lyse fibrin. tPA can serve as an indicator of both myocardial infarction for patients with impaired fibrinolytic systems as well as a marker for type-II diabetes.
Size1 x 96 well
Concentrationn/a
ApplicationsRUO
Other NamestPA, Tissue-type Plasminogen Activator , plasmin, pai-1
Gene, Accession, CAS #n/a
Catalog #TPA39-K01
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Order / More InfoHuman tPA activity ELISA Kit from EAGLE BIOSCIENCES INC.
Product Specific Referencesn/a
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