| 产品详情 |
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| Product Name | Wedelolactone |
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| Description | Purity >98%. MW: 314.25. Wedelolactone is a natural coumestan that irreversibly inhibits IKK in NF-κB signaling pathway. IKK phosphorylates the IκBα protein, which results in the degradation and dissociation of IκBα from NF-κB leading to NF-κB activation. Wedelolactone has anti-inflammatory effect through inhibiting IKK activity and caspase-11 expression. It improves lipid metabolism partly by AMPK activation and up-regulation of expression of PPARα/Lipopoptein Lipase and Low Density Lipoprotein Receptor. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-Methoxy-5,11,12-trihydroxy-coumestan, 1,8,9-Trihydroxy-3-methoxycoumestan, 1,8,9-Trihydroxy-3-methoxy-6H-[1]benzofuro[3,2-c]chromen-6-one 1,8,9-trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one, IKK inhibitor |
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| Gene, Accession, CAS # | CAS: 524-12-9 |
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| Catalog # | B2811-1 |
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| Price | |
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| Order / More Info | Wedelolactone from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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