产品详情 |
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Antigenic Specificity | NCBP1/CBP80 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 10 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NCBP1/CBP80 Polyclonal Antibody. NCBP1, also known as CBP80, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP1 promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Recent evidence has shown that cellular-cap-binding proteins such as NCBP1 associate with influenza virus mRNAs, suggesting that these viral mRNAs may follow the normal cellular pathways for splicing, nuclear export, and translation. |
Immunogen | n/a |
Other Names | RP11-546O6.1, CBP80, MGC2087, NCBP, Sto1, 80 kDa nuclear cap-binding protein; NCBP 80 kDa subunit; nuclear cap-binding protein subunit 1 |
Gene, Accession # | Entrez: 433702, 4686; Uniprot: Q09161, Q3UYV9 |
Catalog # | IHC-00660-T |
Price | |
Order / More Info | NCBP1/CBP80 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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