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| Antigenic Specificity | S100A12 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:500-1:1000, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | S100A12 Polyclonal Antibody. S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated |
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| Immunogen | n/a |
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| Other Names | CAAF1; CAGC; calcium binding protein in amniotic fluid; calgranulin C |
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| Gene, Accession # | Entrez: 6283; Uniprot: P80511 |
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| Catalog # | PA5-51762 |
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| Price | |
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| Order / More Info | S100A12 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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