产品名称 Cytochrome P450 2C19 Inhibitor Screening Kit from CREATIVE BIOMART
产品货号 Kit-2125
产品价格 现货询价,电话:010-67529703
产品规格 100 assays
产品品牌 CREATIVE BIOMART
产品概述
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Product NameCytochrome P450 2C19 Inhibitor Screening Kit
DescriptionCYP2C19 Inhibitor Screening Kit enables rapid screening of drugs and other new chemical entities (NCEs) for compound-CYP2C19 interaction in a reliable, high-throughput fluorescence-based assay. The kit provides a yeast microsomal preparation of human CYP2C19 and cytochrome P450 reductase (CPR) enzymes. The assay utilizes a non-fluorescent CYP2C19 substrate that is converted into a highly fluorescent metabolite detected in the visible range (Ex/Em = 406/468 nm), ensuring a high signal-to-background ratio with little interference by autofluorescence. The kit contains a complete set of reagents sufficient for performing 100 reactions in a 96-well plate format.
Size100 assays
Concentrationn/a
ApplicationsRapid, high-throughput screening of drugs and novel ligands. Development of structure-activity relationship (SAR) models to predict CYP2C19 inhibition liability of novel compounds.Prediction of adverse drug-drug interaction potential and bioavailability for compounds metabolized by CYP2C19.
Other Namesn/a
Gene, Accession, CAS #n/a
Catalog #Kit-2125
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Order / More InfoCytochrome P450 2C19 Inhibitor Screening Kit from CREATIVE BIOMART
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