产品详情 |
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Product Name | Centrinone B |
Description | High affinity and selective PLK4 inhibitor (Ki = 0.6 nM). Exhibits >2000-fold selectivity for PLK4 over Aurora A and Aurora B. Depletes centriole and centrosome levels in vitro. Induces cell cycle arrest in normal human cell lines in a p53-dependent manner. Purity 98%. MW (observed): 631.67 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(1-piperidinyl)-4-pyrimidinamine. LCR 323 |
Gene, Accession, CAS # | CAS: 1798871-31-4 |
Catalog # | 5690/10 |
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Order / More Info | Centrinone B from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 28811500 |
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