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| Product Name | Montelukast (sodium salt) |
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| Description | The CysLTs, LTC4 and LTD4, are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. Their biological effects are transduced by a pair of GPCRs, CysLT1 and CysLT2.{7174,8519,14081} Montelukast (sodium salt) is a potent, selective CysLT1 receptor antagonist sold under the trade name Singulair for the treatment of asthma as well as for the symptoms associated with allergic rhinitis.{6475,6685,14084,14106} It binds to the human CysLT1 receptor with an IC50 of less than 5 nM with no appreciable binding to the CysLT2 receptor.{7174,8519,14081} |
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| Size | 500 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ?MK-476 |
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| Gene, Accession, CAS # | CAS: 151767-02-1 |
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| Catalog # | 10008318-500 |
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| Order / More Info | Montelukast (sodium salt) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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