| 产品详情 |
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| Product Name | Anastrozole |
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| Description | An aromatase/CYP19A1 inhibitor (IC50 = 15 nM for human placental aromatase/CYP19A1); selective for aromatase/CYP19A1 over CYP1A2, CYP2A6, CYP2C9, CYP2D6, and CYP3A (IC50s = 27-650 µM); blocks ovulation in mature female rats and androstenedione-stimulated uterine development in pubertal female rats at 0.1 mg/kg; inhibits peripheral aromatase/CYP19A1 and reduces plasma estradiol concentrations in male pigtailed monkeys at ≥0.1 mg/kg; reduces tumor incidence and the number of tumors well as increases latency to tumor appearance in a rat model of premenopausal mammary tumorigenesis at 0.5 mg/kg |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Anastrol|ICI-D 1033|ZD 1033 |
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| Gene, Accession, CAS # | CAS: 120511-73-1 |
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| Catalog # | 11987-10 |
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| Price | |
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| Order / More Info | Anastrozole from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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