| 产品详情 |
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| Product Name | EX-527 |
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| Description | EX-527 is a cell-permeable, selective inhibitor of SIRT1 (IC50 = 98 nM in vivo, 38nM in vitro) that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 20 uM, 49 uM, > 100 uM and > 100 uM for SIRT2, SIRT3, HDAC and NADase respectively). EX-527 has been used to investigate the relationship between SIRT1-mediated deacetylation of p53, p53 activity, and cell survival following DNA damage. |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | Activator or Inhibitor |
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| Other Names | SIRT 1 inhibitor |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P005-25MG |
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| Price | |
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| Order / More Info | EX-527 from ARBOR ASSAYS, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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