| 产品详情 |
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| Antigenic Specificity | PSAP |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | 1.0 mg/ml |
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| Applications | ELISA, WB, IHC, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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| Immunogen | Purified recombinant fragment of human PSAP (AA: 325-524) expressed in E. Coli. |
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| Other Names | flj00245; glba; mgc110993; prosaposin; prosaposin (variant gaucher disease and variant metachromatic leukodystrophy); prosaposin (variant gaucher disease and variant metachromatic leukodystrophy) variant; prosaposin isoform a preproprotein; prosaposin iso; SAP1; PSAP |
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| Gene, Accession # | PSAP, Gene ID: 5660, SwissProt: P07602 |
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| Catalog # | abx011980 |
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| Price | |
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| Order / More Info | PSAP Antibody from ABBEXA |
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| Product Specific References | n/a |
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