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Product Name | (±)11-HDHA |
Description | (±)11-HDHA is an autoxidation product of DHA in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} DHA is metabolized to 11(S)-HDHA by human platelets and canine retina.{7483,7486,7484,7492} In addition to 11(S)-HDHA, 14(S)-HDHA is also produced by platelets.{7483,7484,7492} 11(S)-HDHA is an inhibitor of U-46619-induced human platelet aggregation and rabbit and rat aortic smooth muscle contraction with IC50 values of about 50, 4.7, and 7.5 µM, respectively.{7484,7481} (±)11-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant PUFA. |
Size | 250 µg |
Concentration | n/a |
Applications | n/a |
Other Names | 11-hydroxy Docosahexaenoic Acid |
Gene, Accession, CAS # | CAS: 87018-59-5 |
Catalog # | 33450-250 |
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Order / More Info | (±)11-HDHA from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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