产品名称 4SC-202 from CAYMAN CHEMICAL COMPANY
产品货号 26175-5
产品价格 现货询价,电话:010-67529703
产品规格 5 mg
产品品牌 CAYMAN CHEMICAL COMPANY
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Product Name4SC-202
DescriptionAn inhibitor of HDAC1-3 and KDM1A; reduces cell viability in a panel of CRC cell lines at 1-10 µM and in patient-derived CRC cell lines at 5 µM; induces cell cycle arrest at the G2/M phase in HT-29 cells and primary human CRC cells at 5 µM; increases apoptosis in HT-29 cells in a concentration-dependent manner, an effect that is enhanced by the Akt inhibitors perifosine and MK-2206; reduces tumor growth in an HT-29 mouse xenograft model at 100 mg/kg, p.o., every other day when administered alone and to an enhanced degree when co-administered with oxaliplatin
Size5 mg
Concentrationn/a
Applicationsn/a
Other Names910462-43-0 4SC202 HDAC3 HDAC-1 2 HDAC2 G-2 HT29 MK2206
Gene, Accession, CAS #CAS: 1186222-89-8
Catalog #26175-5
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