| 产品详情 |
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| Product Name | 4SC-202 |
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| Description | An inhibitor of HDAC1-3 and KDM1A; reduces cell viability in a panel of CRC cell lines at 1-10 µM and in patient-derived CRC cell lines at 5 µM; induces cell cycle arrest at the G2/M phase in HT-29 cells and primary human CRC cells at 5 µM; increases apoptosis in HT-29 cells in a concentration-dependent manner, an effect that is enhanced by the Akt inhibitors perifosine and MK-2206; reduces tumor growth in an HT-29 mouse xenograft model at 100 mg/kg, p.o., every other day when administered alone and to an enhanced degree when co-administered with oxaliplatin |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 910462-43-0 4SC202 HDAC3 HDAC-1 2 HDAC2 G-2 HT29 MK2206 |
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| Gene, Accession, CAS # | CAS: 1186222-89-8 |
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| Catalog # | 26175-25 |
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| Price | |
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| Order / More Info | 4SC-202 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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