| 产品详情 |
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| Antigenic Specificity | Human CD314 (NKG2D) |
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| Clone | 1D11 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
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| Isotype | IgG1, κ |
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| Format | TotalSeq™-C oligomer conjugate |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | PG |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TotalSeq™-C0165 anti-human CD314 (NKG2D). CD314 is a homodimeric C-type lectin-like protein also known as NKG2D. It is expressed on NK cells, CD8+ T cells, γ/δ T cells, and in vitro induced LAK cells. Several molecules have been identified as the ligands for NKG2D, including MHC class-I chain-related protein A (MICA), MICB, and UL16-binding proteins (ULBPs). NKG2D has no intrinsic signaling capacity, but attains this by non-covalent association with DAP10 or DAP12 adaptors. In addition to being a primary activation receptor on NK cells, NKG2D is also a costimulatory receptor for TCR-mediated T cell proliferation and cytokine production. The interaction of NKG2D with its ligands plays a role in the immune surveillance against pathogen and tumor cells, and in the pathogenesis of autoimmune diseases. |
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| Immunogen | n/a |
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| Other Names | NKG2D |
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| Gene, Accession # | Gene ID: 22914 |
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| Catalog # | 320837 |
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| Price | |
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| Order / More Info | Human CD314 (NKG2D) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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