产品详情 |
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Antigenic Specificity | Caspase 5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1:10-1:50, Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase 5 Polyclonal Antibody. This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated |
Immunogen | n/a |
Other Names | ICE(rel)III, ICEREL-III, ICH-3, CASP-5, ICE(rel)-III, TY protease, caspase 5, apoptosis-related cysteine protease, caspase-5, protease ICH-3, protease TY |
Gene, Accession # | Entrez: 838; Uniprot: P51878 |
Catalog # | PA5-24427 |
Price | |
Order / More Info | Caspase 5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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