产品详情 |
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Antigenic Specificity | Caspase 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase 4 Polyclonal Antibody. Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse. |
Immunogen | n/a |
Other Names | ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX |
Gene, Accession # | Entrez: 12363, 837; Uniprot: P49662, P70343 |
Catalog # | PA1-12797 |
Price | |
Order / More Info | Caspase 4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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