| 产品详情 |
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| Antigenic Specificity | Caspase 3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rabbit |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100-1:500, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase 3 Polyclonal Antibody. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcr |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 100008840, 836; Uniprot: P42574, Q8MJC3 |
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| Catalog # | PA1-33035 |
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| Price | |
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| Order / More Info | Caspase 3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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