产品详情 |
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Antigenic Specificity | CD57 |
Clone | HCD57 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM, κ |
Format | Pacific Blue™ conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Pacific Blue™ anti-human CD57. CD57, also known as HNK-1, NK-1, and Leu-7, is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants). |
Immunogen | n/a |
Other Names | HNK-1, NK-1, Leu-7 |
Gene, Accession # | Gene ID: 27087 |
Catalog # | 322316 |
Price | |
Order / More Info | CD57 Antibody from BIOLEGEND |
Product Specific References | PubMed: 21220772,21402893,23243281,23283958,25225458,25225461,25329659,25855354 |
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