| 产品详情 |
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| Product Name | Fidarestat |
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| Description | An aldose reductase inhibitor (IC50 = 0.026 µM); inhibits AKR1B10 (IC50 = 33 µM); decreases sorbitol and myo-inositol levels in the sciatic nerves of STZ-induced diabetic rats (2 mg/kg per day); decreases nerve fiber abnormalities and reverses slowing of MNCV in an STZ-induced diabetic rat model of peripheral neuropathy (2 mg/kg per day); decreases the pain threshold in STZ-induced diabetic mice overexpressing human aldose reductase (4 mg/kg per day); decreases metastasis in a KM20 human colorectal cancer mouse xenograft model (50 mg/kg per day) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | aldos SK860 SK-860 SNK860 AKR1-B10 KM-20 SNK-860 |
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| Gene, Accession, CAS # | CAS: 136087-85-9 |
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| Catalog # | 21756-10 |
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| Price | |
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| Order / More Info | Fidarestat from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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