| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | beta Catenin |
|---|
| Clone | 15B8 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, mouse |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | phycoerythrin (PE) conjugate |
|---|
| Size | 100 Tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | beta Catenin Monoclonal Antibody (15B8), PE, eBioscience™. Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures. AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton. Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases |
|---|
| Immunogen | n/a |
|---|
| Other Names | Cadherin associated protein, Catenin beta 1, CATNB, CTNNB |
|---|
| Gene, Accession # | Entrez: 12387, 1499; Uniprot: P35222, Q02248 |
|---|
| Catalog # | 12-2567-42 |
|---|
| Price | |
|---|
| Order / More Info | beta Catenin Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|