产品详情 |
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Product Name | 1-methyl-D-Tryptophan |
Description | An inhibitor of IDO (IC50 = 7 µM) that is effective in vivo; prevents T-cell anergy triggered by dendritic cells overexpressing IDO in mice; causes regression of tumors and prolongs survival when used in combination with chemotherapy |
Size | 500 mg |
Concentration | n/a |
Applications | n/a |
Other Names | inhibitors cancers D-(+)-1-methyltryptophan D-1-methyltryptophan methyltryptophan D 1 + methyl tryptophan inhibits inhibitions indoleamine 2,3-dioxygenase IDO dioxygenases 2 3 metabolizes kynurenine NAD+ NAD pathways overexpressions tumors tumor-draining draining lymph nodes immunes tolerances growths in vivo mice prevents T cells T-cell anergy dendritic antitumor anti-tumor immunoresponses CD8+ CD8 xenografts chemotherapy regressions survivals humans ovarians carcincomas SKOV-3 SKOV3 SKOV cultures antiviral anti-viral virals indoximod |
Gene, Accession, CAS # | CAS: 110117-83-4 |
Catalog # | 16456-500 |
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Order / More Info | 1-methyl-D-Tryptophan from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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