产品名称 Gemin 2 Antibody from IMMUQUEST LTD.
产品货号 IQ203
产品价格 现货询价,电话:010-67529703
产品规格 0.1ml
产品品牌 IMMUQUEST LTD.
产品概述
产品详情
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Antigenic SpecificityGemin 2
Clone2E17
Host SpeciesMouse
Reactive Speciesmouse, human, Xenopus laevis
IsotypeIgG1
FormatProtein A purified
Size0.1ml
Concentration1mg/ml
ApplicationsFlow Cyt, ICC/IF, ELISA, WB, IP
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionMouse Anti-Gemin 2 [2E17].
ImmunogenHis-Gemin 2 fusion protein (amino acids 12 - 280, starting at 2nd methionine).
Other NamesComponent of gems 2, GEMI2_HUMAN, Gemin-2, gemin2, SIP 1; SIP-1, SIP1, SIP1 delta, SMN interacting protein 1, SMNinteracting protein 1 delta, SMN-interacting protein 1, Survival interacting protein 1; Survival of motor neuron protein interacting protein 1, Survival of motor neuronprotein-interacting protein 1
Gene, Accession #n/a
Catalog #IQ203
Price
Order / More InfoGemin 2 Antibody from IMMUQUEST LTD.
Product Specific ReferencesThe spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Liu Q ( Cell,Sep 1997)PUBMED Sanchez G et al. A novel function for the survival motoneuron protein as a translational regulator. Hum Mol Genet : (2012)PUBMED Wu CY et al. Proteomic assessment of a cell model of spinal muscular atrophy. BMC Neurosci 12:25 (2011). WB ; MousePUBMED Takizawa Y et al. GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination. Nucleic Acids Res. 2010 Aug;38(15):5059-74. doi: 10.1093/nar/gkq271. Epub 2010 Apr 19. WB; HumanPMID: 20403813 Burnett BG et al. Regulation of SMN protein stability. Mol Cell Biol 29:1107-15 (2009). WB ; HumanPUBMED Walker MP et al. SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain. Hum Mol Genet 17:3399-410 (2008). ICC/IF ; MousePUBMED Morency E et al. A novel cell response triggered by interphase centromere structural instability. J Cell Biol 177:757-68 (2007). ICC/IF ; HumanPUBMED RenvoisA B et al. Distinct domains of the spinal muscular atrophy protein SMN are required for targeting to Cajal bodies in mammalian cells. J Cell Sci 119:680-92 (2006)PUBMED
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