| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Lipoteichoic acid |
|---|
| Clone | 55 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG3 |
|---|
| Format | unconjugated |
|---|
| Size | > 200 µg |
|---|
| Concentration | > 200 µg/ml |
|---|
| Applications | frozen sections, FC, immunoassay, IF, WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | The monoclonal antibody 55 recognizes lipoteichoic acid (LTA). LTA, a glycerol phosphate surface polymer, is a component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface. |
|---|
| Immunogen | Microbial mixture of Streptococcus sobrims HG961, HG962, HG970, and HG977 (Ref. 1) |
|---|
| Other Names | LTA |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | HM2048 |
|---|
| Price | |
|---|
| Order / More Info | Lipoteichoic acid Antibody from HYCULT BIOTECH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|