产品名称 VG5Q, Human Antibody from HYCULT BIOTECH
产品货号 HP9037
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 HYCULT BIOTECH
产品概述
产品详情
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Antigenic SpecificityVG5Q, Human
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size100 µg
Concentration100 µg/ml
Applicationsfrozen sections, immunoassay, IP, paraffin sections, WB
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DescriptionThe polyclonal antibody reacts with human VG5Q, a 84 kDa protein. VG5Q functions as an angiogenic factor in promoting angiogenesis and suppression of VG5Q expression inhibits vessel formation. Angiogenic factors are critical to the initiation of angiogenesis and maintenance of the vascular network. Angiogenesis has an essential role in pathological conditions such as cancer and various ischaemic and inflammatory diseases. VG5Q can bind to endothelial cells and promote cell proliferation, suggesting that the protein may act in an autocrine fashion. VG5Q interacts with TWEAK (also known as TNFSF12), another secreted angiogenic factor. VG5Q shows strong expression in blood vessels and is secreted when vessel formation is initiated. VG5Q protein was detected mostly in the cytoplasm and around the nuclei of human microvascular endothelial cells (HMVECs). Furthermore VG5Q is detected in human umbilical vein endothelial cells (HUVECs), human heart fibroblast (HHF) and ovarian cancer cells (OV-3), but low expression was detected in kidney cancer cells (RP-45), HeLa Cells and bladder cancer cells.
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #HP9037
Price
Order / More InfoVG5Q, Human Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
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