| 产品详情 |
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| Antigenic Specificity | BCCIP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100µg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC • WB 1:500 - 1:2000; IHC 1:100 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-BCCIP polyclonal antibody. This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been |
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| Immunogen | BRCA2 and CDKN1A interacting protein |
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| Other Names | TOK1 |
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| Gene, Accession # | Gene ID: 56647, UniProt: Q9P287 |
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| Catalog # | FNab00832 |
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| Price | |
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| Order / More Info | BCCIP Antibody from FINETEST |
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| Product Specific References | n/a |
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