| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | EGFR (pY1125) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | peptide affinity purified |
|---|
| Size | 80 µl, 400 µl |
|---|
| Concentration | n/a |
|---|
| Applications | DB. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. A prototype member of the type 1 receptor tyrosine kinases, EGFR is encoded by the cellular oncogene cerbB1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. Increased production or activation of EGFR has been associated with poor prognosis in a variety of tumors. EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. This EGFR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1125 of human EGFR. |
|---|
| Immunogen | Human EGFR (phospho-Tyr1125). |
|---|
| Other Names | EGFR; epidermal growth factor receptor; erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian; Receptor protein-tyrosine kinase ErbB-1; erbb 1; Receptor tyrosine protein kinase ErbB 1; PIG61; HGNC:3236; ERBB; ERBB1; mENA; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth fac; HER1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1; Epidermal growth factor receptor precursor; kinase EGFR |
|---|
| Gene, Accession # | SwissProt: P00533 |
|---|
| Catalog # | abx031963 |
|---|
| Price | |
|---|
| Order / More Info | EGFR (pY1125) Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|