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Antigenic Specificity | CD275 (B7-H2, B7-RP1, ICOSL) |
Clone | 9F.8A4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human CD275 (B7-H2, B7-RP1, ICOSL). B7-H2, a member of the B7 family and the immunoglobulin superfamily, is a 40 kD protein also known as B7RP-1, B7h, B7-H2, GL50 and ICOS Ligand. Human B7-H2 is expressed by activated monocytes/macrophages and dendritic cells. B7-H2 binds to a CD28-like receptor, inducible costimulator molecule (ICOS, AILIM, CRP-1), which is expressed by activated T cells. The interaction of ICOS with B7-H2 plays an important role in the T cell costimulation pathway. |
Immunogen | Human B7H2-mIg fusion protein |
Other Names | B7-H2, B7H2, B7-RP1, ICOSL |
Gene, Accession # | Gene ID: 23308 |
Catalog # | 329801 |
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Order / More Info | CD275 (B7-H2, B7-RP1, ICOSL) Antibody from BIOLEGEND |
Product Specific References | PubMed: 22732586 |
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