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| Product Name | A 769662 |
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| Description | Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 μM) that displays selectivity towards β1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 μM) and decreases plasma glucose and triglyceride levels in vivo. Also inhibits proliferation of mesenchymal stem cells, and impedes reprogramming of mouse embryonic fibroblasts to iPSCs. Activates autophagy. Purity 98%. MW (observed): 360.39 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile |
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| Gene, Accession, CAS # | CAS: 844499-71-4 |
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| Catalog # | 3336/50 |
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| Order / More Info | A 769662 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21400477, 21421816, 21896918, 21940946, 22932492, 23266956, 23453806, 24080374, 25354528, 25425646, 25698741, 25751140, 26068970, 26434492, 26582390, 27133377, 27566818, 27758862, 28211632, 28613987 |
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