产品名称 A 1210477 from TOCRIS BIOSCIENCE
产品货号 6409/25
产品价格 现货询价,电话:010-67529703
产品规格 25 mg
产品品牌 TOCRIS BIOSCIENCE
产品概述
产品详情
Edit&nbsp
Product NameA 1210477
DescriptionSelective, high affinity Mcl-1 inhibitor (Ki = 454 pM). Disrupts Mcl-BIM complexes (IC50 in low μM range). Also inhibits Mcl-1NOXA interactions. Exhibits no effect on Bcl-XL-Bim or Bcl-X-BCL-Xs interactions. Induces apoptosis in multiple myeloma and non-small cell lung cancer cell lines and exhibits a synergistic effect with NavitoclaxTM to induce apoptosis in vitro. Cell permeable. Purity 98%. MW (observed): 850.04
Size25 mg
Concentrationn/a
Applicationsn/a
Other Names7-[5-[[4-[4-[(Dimethylamino)sulfonyl]-1-piperazinyl]phenoxy]methyl]-1,3-dimethyl-1H-pyrazol-4-yl]-1-[2-(4-morpholinyl)ethyl]-3-[3-(1-naphthalenyloxy)propyl]-1H-indole-2-carboxylic acid
Gene, Accession, CAS #CAS: 1668553-26-1
Catalog #6409/25
Price
Order / More InfoA 1210477 from TOCRIS BIOSCIENCE
Product Specific Referencesn/a
产品资料