产品详情 |
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Antigenic Specificity | OATP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:100, Western Blot: 0.2-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | OATP1 Polyclonal Antibody. The organic anion transporting polypeptides, OATP-A (also designated OATP1, OATP1A2 and SLC21A3) and OATP-C (also designated OATP2, SLC21A6 and LST1), mediate hepatic uptake of cardiac glycosides. The expression of OATP-C, but not OATP-A, is inducible by phenobarbital and pregnenolone-16a-carbonitrile, resulting in the increased capacity of the liver to extract cardiac glycosides from the plasma. OATP-A is expressed in liver and kidney and helps mediate sodium-independent uptake of the anionic steroid conjugates dehydroepiandrosterone sulfate, estradiol-17-glucuronide and prostaglandin. OATP-C is exclusively expressed in liver and is localized to the basolateral hepatocyte membrane. |
Immunogen | n/a |
Other Names | Solute carrier organic anion transporter family member 1A2, OATP, OATP-A, OATP1A2, SLC21A3 |
Gene, Accession # | Entrez: 100034162, 100355617, 100714302, 170698, 282472, 403520, 6579; Uniprot: O35913, P46721 |
Catalog # | PA5-42445 |
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Order / More Info | OATP1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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