产品详情 |
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Antigenic Specificity | OATP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | OATP1 Polyclonal Antibody. The organic anion transporting polypeptides, OATP-A (also designated OATP1, OATP1A2 and SLC21A3) and OATP-C (also designated OATP2, SLC21A6 and LST1), mediate hepatic uptake of cardiac glycosides. The expression of OATP-C, but not OATP-A, is inducible by phenobarbital and pregnenolone-16a-carbonitrile, resulting in the increased capacity of the liver to extract cardiac glycosides from the plasma. OATP-A is expressed in liver and kidney and helps mediate sodium-independent uptake of the anionic steroid conjugates dehydroepiandrosterone sulfate, estradiol-17-glucuronide and prostaglandin. OATP-C is exclusively expressed in liver and is localized to the basolateral hepatocyte membrane. |
Immunogen | n/a |
Other Names | OATP, OATP-1, OATP-A, OATP1A2, Organic anion-transporting polypeptide 1, SLC21A3, SLCO1A2, SO1A2 |
Gene, Accession # | Entrez: 6579; Uniprot: P46721 |
Catalog # | PA5-36610 |
Price | |
Order / More Info | OATP1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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