产品详情 |
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Antigenic Specificity | CD85j (ILT2) |
Clone | HP-F1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | allophycocyanin (APC) conjugate |
Size | 25 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD85j (ILT2) Monoclonal Antibody (HP-F1), APC, eBioscience™. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 10859; Uniprot: Q8NHL6 |
Catalog # | 17-5129-41 |
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Order / More Info | CD85j (ILT2) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20194892, 28197367, 28432285 |
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