产品名称 C5a des Arg, Mouse, Recombinant from HYCULT BIOTECH
产品货号 HC1102
产品价格 现货询价,电话:010-67529703
产品规格 50 µg
产品品牌 HYCULT BIOTECH
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Product NameC5a des Arg, Mouse, Recombinant
DescriptionComplement fragment C5a is a 74-residu glycopolypeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. C5a is a potent chemoattractant and anaphylatoxin that acts on all classes of leukocytes and on many other cell types including endothelial, smooth muscle, kidney, liver, and neural cells. In addition to its proinflammatory effects, C5a has been shown to protect cells against toxic insult and to stimulate proliferation in neurons and hepatocytes, suggesting a wider role for C5a in homeostasis. C5a is rapidly desarginated by serum carboxypeptidase N to the less potent derivate C5a desArg, the first stage in deactivation of anaphylatoxin activity. The C5a desArg form has a different spectrum of bioactivity to intact C5a. Recombinant mouse C5a is His-Tagged and has the following amino acid sequence: MRGSHHHHHHGSDYDIPTTENLYFQGGSNLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYET CEERVARVTIGPLCIAFNECCTIANKIRKESPHKPVQLG. The molecular weight of the protein is 12 kg/mol. .
Size50 µg
ConcentrationLyophilized product in 0.005% Tween 80, 2mM reduced L-glutathion, 0.2mM oxidized L-glutathion and 0.1M Tris-Cl buffer, pH 8.0, containing at least 50 µg murine C5a desArg.
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Other Namesn/a
Gene, Accession, CAS #n/a
Catalog #HC1102
Price
Order / More InfoC5a des Arg, Mouse, Recombinant from HYCULT BIOTECH
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