产品名称 Basophils, Human Antibody from HYCULT BIOTECH
产品货号 HM2279
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 HYCULT BIOTECH
产品概述
产品详情
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Antigenic SpecificityBasophils, Human
Clone2D7
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size100 µg
Concentration100 µg/ml
Applicationsfrozen sections, FC, IF, paraffin sections, WB
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThe monoclonal antibody 2D7- is a specific marker for basophils detecting- a basophil-specific protein of 7.2-7.5 kDa localized in secretory granules. Activated basophils- have been shown to have a reduced staining with the 2D7 antibody consistent with localization of the antigen- to secretory granules. Basophils are multifunctional haematopoietic cells that- secrete a wide variety of proinflammatory- agents upon activation such as histamine and cytokines. Moreover, basophils can induce IgE production by B cells. Under normal conditions basophils are primarily produced in the bone marrow, whereas mature basophils reside in the circulation and can enter tissues at sites of inflammation. Both basophils and mast cells have been implicated in the pathogenesis of allergic inflammation due to the abundant expression of high affinity receptors for IgE. The 2D7 antibody can be used- as a sensitive and precise marker for human basophils- and does not react with lymphocytes, monocytes, eosinophils, neutrophils- or mast cells in immunohistochemistry. Moreover, the antibody is suitable for western blot analysis of the 2D7 antigen.
ImmunogenLysate of purified basophils
Other Namesn/a
Gene, Accession #n/a
Catalog #HM2279
Price
Order / More InfoBasophils, Human Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
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