产品名称 Arginase I, Human Antibody from HYCULT BIOTECH
产品货号 HM2324
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 HYCULT BIOTECH
产品概述
产品详情
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Antigenic SpecificityArginase I, Human
CloneD1.2
Host SpeciesMouse
Reactive Specieshuman, horse - weak, sheep
IsotypeIgG1
Formatunconjugated
Size100 µg
Concentration100 µg/ml
ApplicationsFC, immunoassay, WB
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DescriptionMonoclonal antibody D1.2 reacts specifically with Arginase I, the final enzyme in the urea cycle, which is responsible for the hydrolysis of arginine to urea and ornithine. The highest concentration of the enzyme is present in the liver in which the bulk of ureagenesis occurs. Two types of arginases are known: Arginase I and II. The cytosolic enzyme found primarily in liver is Arginase I, a 35 kD protein that circulates as trimer. Arginase II is exclusively located in the mitochondrion. Arginase I is next to the liver in man also expressed by mature fetal and adult red blood cells and activated monocytic cells. During inflammation induction of Arginase I by inflammatory cytokines in monocytic cells is considered to lead to a local depletion of arginine resulting in a microenvironment that prevents nitric oxide production and arginine dependent T cell function. Arginase II is expressed by kidney, nucleated red blood cells, brain, spinal cord, gastro-intestinal tract, mammary gland and prostate. Enhanced circulating Arginase I levels have been reported after surgery, following haemorrhage and in asthmatic patients. Measurement of circulating Arginase I has been used experimentally as rapid marker for liver injury.
ImmunogenPeptide D14967-1-1t/m6
Other Namesn/a
Gene, Accession #n/a
Catalog #HM2324
Price
Order / More InfoArginase I, Human Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
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