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 | Antigenic Specificity | Alpha-Catenin, Human | 
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 | Clone | 1G5 | 
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 | Host Species | Mouse | 
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 | Reactive Species | human | 
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 | Isotype | IgG1 | 
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 | Format | unconjugated | 
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 | Size | 100 µg | 
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 | Concentration | 100 µg/ml | 
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 | Applications | FC, IF, IP, WB | 
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 | Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. | 
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 | Description | The monoclonal antibody 1G5 reacts with human alpha-catenin. Alpha-catenin belongs together with beta- and gamma-catenin to the catenin family. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Cadherins are single pass, type I transmembrane proteins that are localized in the adherens junction. To be fully functional, the cadherin cytoplasmic domain must be linked to the actin cytoskeleton through a group of proteins termed catenins: alpha-catenin, beta-catenin and plakoglobin. Alpha catenin interacts with the cadherin indirectly via interactions with beta-catenin or plakoglobin. | 
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 | Immunogen | n/a | 
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 | Other Names | n/a | 
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 | Gene, Accession # | n/a | 
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 | Catalog # | HM2118 | 
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 | Price |  | 
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 | Order / More Info | Alpha-Catenin, Human Antibody from HYCULT BIOTECH | 
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 | Product Specific References | n/a | 
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