| 产品详情 |
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| Antigenic Specificity | Asc (Tyr-144), phospho-specific |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat, mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | WB, ELISA, ICC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This antibody was cross-adsorbed to unphosphorylated Asc (Tyr-144) peptide before affinity purification using phospho-Asc (Tyr-144) peptide (without carrier). The antibody detects phosphorylated Asc (Tyr-144) in the inflammasome. In J774 macrophage cells primed with LPS and treated with nigericin, the antibody colocalized with an inflammasome marker, caspase-1 inhibitor (FAM-YVAD-FMK). In addition, the antibody detects a 20 kDa Asc protein in western blots of J774A.1 mouse macrophages treated with pervanadate. |
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| Immunogen | Asc (Tyr-144) phospho-peptide (coupled to KLH) corresponding to amino acid residues surrounding Tyr-144 in mouse Asc. This peptide sequence is highly conserved in human and rat Asc. |
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| Other Names | Caspase, PYCARD, AIM, ASC, CARD5, TMS1 |
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| Gene, Accession # | Q9EPB4 |
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| Catalog # | AP5631 |
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| Price | |
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| Order / More Info | Asc (Tyr-144), phospho-specific Antibody from ECM BIOSCIENCES LLC |
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| Product Specific References | n/a |
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