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Product Name | Cholesteryl Linoleate Hydroperoxides |
Description | Cholesteryl linoleate hydroperoxides are derived from the autoxidation of cholesteryl linoleate and contain a mixture of racemic 9- and 13-HpODE cholesteryl esters. Oxidative modification of LDL is suggested to play an important role in atherosclerosis. (±)9- and (±)13-HODE cholesteryl esters were originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.{2227,2228} Later studies determined that 15-LO, from rabbit reticulocytes and activated human monocytes, oxygenates cholesteryl linoleate to both 9- and 13-hydroperoxy linoleate cholesteryl esters.{1126,2412} Cholesteryl ester hydroperoxides may be transferred from LDL to HDL, reduced to the corresponding hydroxides, and cleared via the liver.{6527,3832} |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | autoxidation atherosclerosis LDL HDL hydroperoxy fatty acids |
Gene, Accession, CAS # | n/a |
Catalog # | 48001-500 |
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Order / More Info | Cholesteryl Linoleate Hydroperoxides from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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